Haopeng Sun Selected Research

Biomarkers (Surrogate Marker)

3/2024	Butyrylcholinesterase-Activated Near-Infrared Fluorogenic Probe for In Vivo Theranostics of Alzheimer's Disease.
12/2022	Design, synthesis, and biological evaluation of aromatic tertiary amine derivatives as selective butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease.
1/2022	Design, synthesis, biological evaluation and molecular modeling of N-isobutyl-N-((2-(p-tolyloxymethyl)thiazol-4yl)methyl)benzo[d][1,3] dioxole-5-carboxamides as selective butyrylcholinesterase inhibitors.

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Haopeng Sun Research Topics

Disease

37	Alzheimer Disease (Alzheimer's Disease) 04/2024 - 01/2016
31	Neoplasms (Cancer) 02/2024 - 05/2012
11	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2023 - 05/2017
4	Inflammation (Inflammations) 05/2024 - 11/2014
4	Parkinson Disease (Parkinson's Disease) 12/2023 - 01/2022
4	Hypoxia (Hypoxemia) 01/2022 - 12/2015
3	Cognitive Dysfunction 04/2024 - 11/2021
3	Prostatic Neoplasms (Prostate Cancer) 02/2023 - 01/2020
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 05/2024 - 01/2020
2	Mitochondrial Diseases (Mitochondrial Disease) 05/2024 - 01/2020
2	Sarcoma (Soft Tissue Sarcoma) 10/2023 - 01/2020
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023 - 04/2020
2	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 01/2020
2	Metabolic Diseases (Metabolic Disease) 10/2021 - 10/2020
2	Carcinogenesis 02/2021 - 01/2020
2	Cardiac Arrhythmias (Arrythmia) 06/2014 - 01/2014
1	Disease Progression 04/2024
1	Huntington Disease (Huntington's Disease) 05/2023
1	Breast Neoplasms (Breast Cancer) 02/2023
1	Vomiting 01/2023
1	Glioblastoma (Glioblastoma Multiforme) 04/2022
1	Parkinsonian Disorders (Parkinsonism) 01/2022
1	Pathologic Processes 01/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 10/2021
1	Bites and Stings (Sting) 02/2021
1	Infections 02/2021
1	Substance-Related Disorders (Drug Abuse) 01/2021
1	Bipolar Disorder (Manic Depressive Psychosis) 01/2021
1	Dementia (Dementias) 01/2021

Drug/Important Bio-Agent (IBA)

16	ButyrylcholinesteraseIBA 04/2024 - 05/2017
7	Proteins (Proteins, Gene)FDA Link 05/2024 - 01/2015
7	LigandsIBA 12/2022 - 01/2017
6	EnzymesIBA 05/2023 - 09/2013
5	Phosphotransferases (Kinase)IBA 12/2023 - 04/2020
5	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2021 - 10/2018
4	Acetylcholine (Acetylcholine Chloride)FDA Link 04/2024 - 01/2021
4	AcetylcholinesteraseIBA 12/2022 - 01/2016
4	Tacrine (Cognex)FDA Link 01/2020 - 01/2017
3	Biomarkers (Surrogate Marker)IBA 03/2024 - 01/2022
3	CytokinesIBA 02/2024 - 02/2021
3	Therapeutic UsesIBA 02/2024 - 01/2021
3	Aldo-Keto ReductasesIBA 02/2023 - 08/2022
3	Hormones (Hormone)IBA 02/2023 - 10/2020
3	Monophenol Monooxygenase (Tyrosinase)IBA 01/2023 - 01/2018
3	Cholinergic Agents (Cholinergics)IBA 01/2021 - 05/2017
3	Cholinesterases (Cholinesterase)IBA 12/2020 - 12/2018
2	Leucine (L-Leucine)FDA Link 12/2023 - 01/2023
2	AnthracyclinesIBA 02/2023 - 01/2023
2	Histone Deacetylase 6IBA 01/2023 - 12/2021
2	Glycogen Synthase KinasesIBA 11/2021 - 01/2021
2	Glycogen Synthase Kinase 3IBA 01/2021 - 12/2020
2	Miconazole (Monistat)FDA LinkGeneric 01/2021 - 01/2018
2	cinnamic acidIBA 01/2020 - 12/2018
2	Carbolines (Beta-Carbolines)IBA 01/2020 - 01/2018
2	beta-lapachoneIBA 03/2016 - 07/2014
1	Riluzole FDA LinkGeneric 05/2024
1	Glutamic Acid (Glutamate)FDA Link 05/2024
1	Amyloid (Amyloid Fibrils)IBA 04/2024
1	LipopolysaccharidesIBA 04/2024
1	Immune Checkpoint ProteinsIBA 02/2024
1	Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA 12/2023
1	Guanidine (Guanidine Nitrate)FDA Link 10/2023
1	Tyrosine (L-Tyrosine)FDA Link 10/2023
1	SaltsIBA 10/2023
1	ThiazolesIBA 10/2023
1	KynurenineIBA 05/2023
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 05/2023
1	laquinimodIBA 05/2023
1	Mixed Function Oxygenases (Monooxygenases)IBA 05/2023
1	diazonaphthalenedisulfonic acid (NDS)IBA 05/2023
1	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2023
1	ErbB Receptors (EGF Receptor)IBA 01/2023
1	Amyloid beta-PeptidesIBA 01/2023
1	Phosphodiesterase 4 InhibitorsIBA 01/2023
1	osimertinibIBA 01/2023
1	AminesIBA 12/2022
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 04/2022
1	Phosphodiesterase InhibitorsIBA 03/2022
1	tetramethylpyrazineIBA 01/2022
1	resorcinol (resorcin)IBA 01/2022
1	benzamideIBA 01/2022
1	Aldo-Keto Reductase Family 1 Member C3IBA 01/2022
1	Rivastigmine (Exelon)FDA LinkGeneric 01/2022
1	neuromelaninIBA 01/2022
1	2-chloro-5-nitrobenzanilideIBA 01/2022
1	Glycogen Synthase Kinase 3 betaIBA 12/2021
1	Neuroprotective AgentsIBA 11/2021
1	InterferonsIBA 02/2021
1	Interferon Type IIBA 02/2021
1	Antihypertensive Agents (Antihypertensives)IBA 01/2021
1	Proteolysis Targeting ChimeraIBA 01/2021
1	Hypnotics and Sedatives (Sedatives)IBA 01/2021
1	AlkaloidsIBA 01/2021
1	Scopolamine (Hyoscine)FDA Link 01/2021
1	Cocaine (Cocaine HCl)IBA 01/2021

Therapy/Procedure

10	Therapeutics 05/2024 - 01/2015
2	Immunotherapy 02/2024 - 02/2021
2	Drug Therapy (Chemotherapy) 02/2023 - 01/2023
1	Precision Medicine 03/2024
1	Ligation 01/2022